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8.13. GnRH antagonist treatment of malignant adrenocortical tumors

M Doroszko , M Chrusciel , J Stelmaszewska , T Slezak , S Anisimowicz , U Plockinger , M Quinkler , M Bonomi , S Wolczynski , I Huhtaniemi , J Toppari , NA Rahman

To read the full abstract: Endocr Relat Cancer. 2019; 26(1): 103117.Incidence of adrenocortical carcinomas shows a bimodal distribution, being more common in children <10 years and in adults aged 4050 years. Their prognosis is poor, with only 1025% 5-year survival. Ectopic expression of LHCGR and GNRHR has been reported in ACTH-independent adrenal hyperplasia ...

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ey0019.3-2 | Thyroid hormone action | ESPEYB19

3.2. Congenital hypothyroidism and hyperthyroidism alters adrenal gene expression, development, and function

K Patyra , C Lof , H Jaeschke , H Undeutsch , HS Zheng , S Tyystjarvi , K Puławska , M Doroszko , M Chruściel , BM Loo , R Kurkijarvi , FP Zhang , CJ Huang , C Ohlsson , A Kero , M Poutanen , J Toppari , R Paschke , N Rahman , I Huhtaniemi , J Jaaskelainen , J Kero

Thyroid. 2022 Apr;32(4):459-471. doi: 10.1089/thy.2021.0535. PMID: 35044245Brief Summary: This study combines animal model and patient cohort data on the effect of hyperthyroidism and hypothyroidism at birth on adrenal gland development and function. The data revealed reciprocal effects of neonatal hyper- and hypothyroidism on adrenal development, activity of the adrenal steroidogenic pathway a...

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ESPE Yearbook of Paediatric Endocrinology

8.13. GnRH antagonist treatment of malignant adrenocortical tumors

3.2. Congenital hypothyroidism and hyperthyroidism alters adrenal gene expression, development, and function

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